منابع مشابه
Kojic Acid Derivatives
Melanin is one of the most important pigments which exist ubiquitously from microorganisms to plants and animals. It is secreted by melanocyte cells and determines the color of skin and hair in mammalians. It protects the skin from photocarcinogenesis by absorbing UV sunlight and removing reactive oxygen species (ROS) (Gupta, 2006; Kim, 2005; Sapkota, 2011). It is formed by enzymatically cataly...
متن کاملThe Biosynthesis of Kojic Acid
Barker, S. B., Kiely, C. E., Dirks, H. B., Klitgaard, H. M., Wang, S. C. & Wawzonek, S. (1950). J. Phlarmacol. 99, 202. Barnes, J. H., Elks, J., Stephens, F. F. & Waller, G. J. (1953). J. chem. Soc. p. 764. Cortell, R. E. (1949). J. clin. Endocrin. 9, 955. Datta, R. L. & Prosad, N. (1917). J. Amer. chem. Soc. 39, 443. Frieden, E. & Winzler, R. J. (1949). J. biol. Chem. 179, 423. Kalb, L., Schwe...
متن کاملCarcinogenicity studies in rodents and ripazepam, a minor tranquilizing agent.
The carcinogenesis potential of ripazepam , a benzodiazepine derivative, was studied in mice and rats for 78 and 104 weeks, respectively. Groups of 50 male and 50 female CD1 mice and CD rats each were given doses of 15 and 150 mg/kg of ripazepam in the diet. Survival rates were adequate for statistical analysis. Significant suppression of body weight gains occurred in rats but not in mice given...
متن کاملIn Vitro Photochemical Induction of Kojic Acid-DNA Adducts
Objective: Kojic Acid (KA) is a natural substance which inhibits skin melanin production and, when used alone or in combination with other compounds, is effective in reducing pigmentation in melasma patients. KA was classified by IARC as presenting limited evidence of carcinogenicity based largely on a single study showing thyroid neoplasms. More recently KA has been shown to be carcinogenic in...
متن کاملNano silica sulfuric acid catalyzed synthesis of 2-substituted aryl (indolyl) kojic acid derivatives
Nano silica sulfuric acid as a solid acid, was described to be an effective catalyst for one-pot three-component reaction of kojic acid, aryl aldehydes and indoles for the preparation of 2-substituted aryl (indolyl) kojic acid derivatives. The catalyst was prepared by combination of chlorosulfonic acid to nano silica gel. The size of nanoparticles were observed with SEM.All prepared compounds w...
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ژورنال
عنوان ژورنال: Mycotoxins
سال: 2003
ISSN: 0285-1466,1881-0128
DOI: 10.2520/myco1975.2003.suppl3_59